Solskjaer has confirmed Phil Jones, Luke Shaw and Axel Tuanzebe did not travel to Germany for the tie at Stadion Koln.
James Garner and Ethan Galbraith will also be with the team.
Youth-team skipper Teden Mengi is on the list, along with fellow defender Ethan Laird, who has already make two appearances in the competition this season.
Dean Henderson who returns from a loan spell at Sheffield United has been left at home.
Goalkeepers: David De Gea, Sergio Romero, Lee Grant, Nathan Bishop.
Defenders: Eric Bailly, Diogo Dalot, Tim Fosu-Mensah, Ethan Laird, Victor Lindelof, Harry Maguire, Teden Mengi, Aaron Wan-Bissaka, Brandon Williams.
Midfielders: Andreas Pereira, Bruno Fernandes, Fred, Ethan Galbraith, James Garner, Daniel James, Jesse Lingard, Juan Mata, Nemanja Matic, Scott McTominay, Paul Pogba.
Forwards: Anthony Martial, Marcus Rashford, Tahith Chong, Mason Greenwood, Odion Ighalo
